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1.
Benha Medical Journal. 2008; 25 (2): 135-148
in English | IMEMR | ID: emr-112119

ABSTRACT

Suppurative otitis media is a common disease affecting all ages and both sexes. Development of bacterial resistance is very common making difficulties in management of both acute suppurative otitis media [Ac s o m] and chronic suppurative otitis media [Ch s o m] cases. More recently, interest in honey as a therapeutic agent has undergone a renaissance. Honey is used for management of infected wounds, burns and exhibited excellent results against Gram +ve and Gram-ve organisms in vitro and in some in vivo studies on infected wounds. To compare results of using Al-sidr honey and antibiotics for treatment of acute and chronic suppurative otitis media. Culture and sensitivity of honey, using agar incorporation technique to prepare plates containing serial dilutions of honey to detect MIC for the selected organisms. Preparing honey as ear drops 10% more than MIC. One hundred twenty patients, 60 with [Ac s o m] and 60 with [Ch s o m] divided into 2 groups, Group 1 honey group divided into Group 1A: 30 patients with ac s o m [10 with Streptococcus pneumonia, 10 with Haemophilus influenza and 10 with Moraxtila catarrhalis] and Group IB 30 patients with ch s o m [10 with Pseudomonas aeroginosa, 10 iuith KLebsiella and 10 with Proteus] treated by Al-sidr honey local ear drops. Group 2 antibiotic group same distribution as group 1 and treated by antibiotics. There is significant differences between using honey and traditional approach for antibiotic use even after CIS without side effects or complications. We recommend start thinking to use Al-sidr honey as local ear drops for management policies of suppurative otitis media


Subject(s)
Humans , Male , Female , Honey , Anti-Bacterial Agents , Treatment Outcome , Otitis Media, Suppurative/microbiology , Disease Management
2.
Benha Medical Journal. 2008; 25 (2): 149-160
in English | IMEMR | ID: emr-112120

ABSTRACT

Peritonstilar infection describes a spectrum of diseases that range from peritonsillar cellulitis to peritonsillar abscess. To assess the disease pattern and its management and to examine the role of routine bacterial cultures. We carried out a prospective study with 30 patients diagnosed with peritonsillar infection. Twenty two patients with peritonsillar abscess [PTA] and eight cases with peritonsillar cellulitis [PTC] of these eight cases 4 cases resolved with medicine and the other 4 cases progressed to [PTA] so finally we have 26 cases with [PTA], for these needle aspiration is done from the most prominent point and if pus came we progressed to incision and drainage wider local or general anesthesia according to patients condition. Around 3ml of pus is taken and sent to lab. Immediately and processed for culture for aerobic and anaerobic organisms. Then these 26 cases of PTA divided into 2 groups each one contains 13 cases group I received ampicillin plus metronidazole and group 2 received 3rd generation cephalosporins plus metronidazole. We assessed number of bacteria per aspirate as well as type of bacteria present aerobic or anaerobic. After results of c/s came we assessed the need to change antibiotics. Lastly we assessed length of stay in the hospital for both groups according to antibiotics used. We found 2.1 bacteria per aspirate. Bacteria grown from all aspirates with culture positivness 100%. We found 55 bacteria grown from 26 cases of PTA, with 28 aerobes and 27 anaerobic organisms. There were need to change antibiotics in 3 cases of group I and in 5 cases of group 2 with significant difference. Mean length of stay in group 1 was 4 +/- 3 while in group 2 was 5 +/- 2 with non significant differences between both groups. 1-Culture and sensitivity of pus drained from PTA should be done. 2-We should use drugs for anaerobic organisms on treatment of peritonsillar infections


Subject(s)
Humans , Male , Female , Biopsy, Fine-Needle , Culture Techniques , Microbial Sensitivity Tests , Peritonsillar Abscess/therapy , Cephalosporins , Metronidazole , Treatment Outcome
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